Ask the
GLP-1 Expert

Get clear answers to the most common questions about GLP-1 medications. Learn how they work, what to expect, and how they can help with weight loss.

Most Asked Questions

Do I really need a dietitian if I am taking a GLP-1?

While GLP-1 medications help manage appetite, they don’t tell you what to eat or how to keep your muscles strong. Pairing a structured food plan with your medication helps you lose weight, feel better, and experience fewer side effects. Clients who work with a dietitian and follow a personalized food plan tend to preserve muscle mass and see better long-term results, instead of regaining weight when the medication is stopped.

Which GLP-1 medication produces the most weight loss?

Clinical trials show that tirzepatide (found in Mounjaro and Zepbound) often leads to more significant weight loss than semaglutide (found in Ozempic and Wegovy). However, the best choice depends on your health, goals, and what your prescriber recommends. Insurance coverage is also a factor, as some medications are more easily covered for diabetes management or weight loss.

How long will I need to stay on a GLP-1?

The length of time you stay on a GLP-1 depends on your goals and progress. Many people use GLP-1s to help build healthier eating habits while appetite is reduced. Once those habits are in place, you might be able to taper off the medication. Without long-term habit changes, weight tends to return after stopping. Together, we’ll work to create lasting changes during your time on the medication.

Can you prescribe the GLP-1 medication for me?

As a Registered Dietitian, I don’t prescribe medications. However, I can help you understand your options and prepare the right questions for your prescribing provider. Your prescription will come from a physician, nurse practitioner, or telehealth provider.

Is your program done in person or can I do it remotely?

The program is fully remote and designed to be convenient for your lifestyle. All consultations, check-ins, and follow-ups are done by phone. This makes it easy for people in different time zones or with busy schedules to stay on track.

What does working with you actually look like?

We start with an initial consultation to discuss your health history, eating habits, lifestyle, and goals. I’ll then create a customized food plan to work alongside your GLP-1. We’ll focus on protein targets, hydration, managing side effects, and preserving muscle. We’ll check in regularly to adjust your plan as your treatment progresses.

What side effects should I expect, and can diet help manage them?

The most common side effects are nausea, constipation, and fatigue, especially in the first few weeks or after a dose increase. Your diet plays a big role in managing these. Eating smaller portions, avoiding greasy foods, focusing on easy-to-digest meals, and staying hydrated can help. I guide you through managing these side effects with food, so you don’t just have to wait them out.

What if I’m struggling with constipation or digestive changes on a GLP‑1?

It’s common to notice changes in digestion when you start a GLP‑1 medication, including constipation. These drugs slow stomach emptying and reduce appetite, and that can make bowel movements harder or less frequent. Drinking plenty of water, eating fiber‑rich foods like vegetables, fruits, and whole grains, and gentle movement can help your system stay regular. If constipation becomes uncomfortable or persistent, your provider can suggest safe strategies or adjust your plan to help. This kind of support makes it easier to stick with your goals while staying comfortable.

Will I lose muscle on a GLP-1?

Losing muscle is a risk when you lose weight too quickly without enough protein or exercise. A good diet plan helps protect your muscles, so you lose fat instead. I focus on protein targets and structuring your food plan to preserve muscle while you’re losing body fat.

How much protein do I need while on a GLP-1?

Most adults on GLP-1s need to aim for 1.2 to 1.6 grams of protein per kilogram of body weight per day. Since GLP-1s reduce food intake, hitting your protein targets requires careful planning. Protein should come first at each meal to make sure you meet your goals.

What should I eat on a GLP-1 to maximize results?

Focus on protein at every meal (eggs, poultry, fish, Greek yogurt, legumes), build around non-starchy vegetables for fiber, add healthy fats in moderation, and limit processed or sugary foods. Smaller, more frequent meals can help when your appetite and stomach capacity are reduced. We’ll tailor the specifics to your needs, ensuring the plan fits your lifestyle.

Where can I get a GLP-1 prescription?

You can get a GLP-1 prescription from your primary care physician, an endocrinologist, a weight loss specialist, or a telehealth provider. Telehealth options like Mochi Health make it easier than ever to consult online and get prescriptions. 

How much do GLP-1 medications cost, and is there any way to reduce that?

Without insurance, brand-name GLP-1s can cost $900 to $1,400 per month. Insurance costs depend on your diagnosis; diabetes coverage is often broader than weight loss coverage. Many medications offer savings cards to help reduce the cost for eligible patients. The cost of compounded options can be lower, but be aware that quality may vary. Be sure to discuss your options with your provider.

What happens when I stop taking a GLP-1?

When you stop taking a GLP-1, your appetite will likely return to its usual level, and weight gain can occur if lifestyle habits haven’t changed. Research shows that people who don’t change their eating and exercise habits tend to regain the weight within one to two years. That’s why I work with you to build sustainable habits while the medication is helping.

Can I take a GLP-1 if I have type 2 diabetes?

Yes! GLP-1 medications like Ozempic and Mounjaro are commonly prescribed for type 2 diabetes to help manage blood sugar and support weight loss. If you have type 2 diabetes, these medications can be a great way to manage both blood sugar and weight at the same time.

Are GLP-1s safe long-term?

Yes, GLP-1s are generally safe for long-term use, especially when prescribed for type 2 diabetes. Your doctor will monitor you to ensure the medication is working properly and adjust your treatment plan as needed. Alongside this, I’ll work with you to make sure your food and exercise plans keep you on track for sustainable results.

I have been on a GLP-1 for a few months and weight loss has slowed. Is that normal?

Yes, this is completely normal. Many people experience rapid weight loss in the first few months, followed by a plateau. This usually happens as the body adjusts, and it can also mean your calorie needs have decreased. This is a great time to review your food plan and check if your protein goals are being met. It’s also a good time to talk with your prescribing provider to see if a dose adjustment might be helpful.

Do I need to exercise while on a GLP-1?

Exercise is not required for weight loss with GLP-1s, but it helps preserve muscle and improve the quality of weight lost. Resistance training is especially important, as it helps ensure you’re losing fat rather than muscle. I recommend at least two sessions per week, tailored to your fitness level, to support your weight loss and health.

Can GLP-1s help with binge eating or emotional eating?

Yes, research suggests that GLP-1s can reduce food cravings and emotional eating. Many people notice a decrease in the urge to binge eat and feel more in control of their eating habits. However, medication alone isn’t enough. Working with a therapist who specializes in eating behavior, along with a structured food plan, gives the best results for long-term success.

I submitted a question, when will I hear back?

I respond to questions as quickly as I can, usually within 24 hours. If you're waiting on a response, please know I’m working to get back to you. Meanwhile, feel free to review the FAQs or the resources on the website for additional guidance.

I am pregnant or planning to become pregnant. Can I stay on a GLP-1?

GLP-1 medications are usually not recommended during pregnancy. If you are planning to get pregnant, speak to your doctor before continuing. Some medications, like Ozempic and Wegovy, are usually stopped at least 2 months before trying to get pregnant. If you become pregnant while taking a GLP-1, contact your OB/GYN and prescribing doctor right away. Also, weight loss may improve fertility for some women, especially with PCOS, so it is important to plan ahead.

Can I drink alcohol while on a GLP-1?

Usually, yes, but it is best to keep it limited. Alcohol is not known to have a direct interaction with GLP-1 medications, but it may affect you faster because you may be eating less and digesting more slowly. It can also add extra calories and make nausea, reflux, or stomach discomfort worse. If you have a history of pancreatitis, liver issues, heavy alcohol use, or blood sugar problems, ask your doctor what is safe for you.

Are GLP-1s injections? Is that hard to do?

Most GLP-1 medications are injections, but they usually come in a simple pen and are much easier than people expect. Many are taken once a week with a very small needle, usually in the stomach, thigh, or upper arm. Most people feel nervous at first, but get comfortable quickly. If injections are a major concern, ask your provider if an oral option makes sense for you.

Can I take a GLP-1 if I don’t have diabetes?

Yes. You do not need to have diabetes to take certain GLP-1 medications. Some GLP-1 medications, like Wegovy and Zepbound, are approved for weight loss in people without diabetes. However, not every GLP-1 is approved for weight loss. For example, Ozempic is mainly used for type 2 diabetes, while Wegovy is the semaglutide brand approved for weight management. The best option depends on your health history, weight, goals, and what your provider recommends.

How does a GLP-1 actually work in the body?

GLP-1 is a hormone your body naturally makes after you eat. GLP-1 medications copy that hormone in a stronger, longer-lasting way. They help you feel full faster, stay full longer, and think about food less. They also slow digestion and help with blood sugar control. For many people, this makes it easier to eat less and follow a plan.

Do I need supplements while on a GLP-1?

Not everyone needs supplements. Because GLP-1s can lower your appetite, you may eat less than usual. This can make it harder to get enough protein, fiber, vitamins, and minerals. Some people may benefit from things like protein, fiber, electrolytes, vitamin D, B12, iron, magnesium, or a multivitamin. The right supplement depends on your food intake, symptoms, labs, and health history.

Can I take a GLP-1 with my other medications?

Often, yes, but it depends on the medication. GLP-1s can interact with some medicines, especially diabetes medications like insulin or sulfonylureas, because they may increase the risk of low blood sugarThey can also slow digestion, which may affect how some pills are absorbed.
Before starting a GLP-1, tell your provider about all medications and supplements you take so they can check for safety and adjust doses if needed.

What do you want to know?

If you have questions, feel free to submit them here.